Measurements of Retinal Bifurcations
The vascular network is determined by a complex set of physiological demands, making
it difficult to understand, and no fully comprehensive theory has yet emerged. Several
authors have proposed that the arterial branching pattern is governed by optimality
principles: minimization of the lumen surface, lumen volume, pumping power and endothelial
drag. The branching angles and relative diameters are proposed to be so-designed
to optimize the efficiency of the entire vascular network – bearing in mind the
fundamental requirement to service the requirements of the organ.
Automated Measurements of Retinal Bifurcations
A new automated procedure is developed to measure retinal bifurcation features: blood vessel width and blood vessel angles. The automated measurements agree with the theoretical prediction measurements with slightly different bias. The automated method can measure a large number of retinal bifurcations very rapidly, and may be useful in correlating bifurcation geometry with clinical condition.
Semi-manual Rectangle Mark-up Technique
A new computerized tool for accurate manual measurement of features of retinal bifurcation geometry, designed for use in investigating correlations between measurement features and clinical conditions. The tool uses user-placed rectangles to measure the vessel width, and lines placed along vessel center lines to measure the angles. The new tool shows better agreement with the theoretical predictions than a simpler manual method published in the literature.
The algorithm was designed using the MATLAB software package It consist of two steps;
labelling and marking of retinal bifurcations.
Click here to download the Semi-manual Rectangle mark-up Technique.
Click here to download the instruction of using this technique.